DIN Standards Committee Materials Testing
Nanotechnologies - Guidelines for sample preparation, detection, identification and characterization by spICP-MS and EM-EDX of nano-objects in inorganic additives incorporated in food matrices
Abstract
This document provides guidance to the food industry, service providers and control laboratories on methodologies to be used for sample preparation, detection, identification and measurement of nano objects in inorganic food additives incorporated in food matrices. Electron microscopy combined with energy dispersive X-ray spectroscopy (EM-EDX) and inductively coupled plasma mass spectrometry (ICP-MS) operated in single particle mode (spICP-MS) are the selected measurement methodologies to provide information on (i) the chemical composition and (ii) number-based particle size distribution of the nano-objects. Special attention is given to the sample preparation, including matrix digestion, sample extraction and dilution steps to be used according to the combination of (i) the chemical nature of the food additive, (ii) the type of food matrix and (iii) the analytical technique of choice (EM-EDX or spICP-MS).
Begin
2025-03-04
WI
00352044
Planned document number
CEN/TS 18267
Responsible national committee
NA 062-08-17 AA - Nanotechnologies
Responsible european committee
CEN/TC 352/WG 4 - Manufactured nano-objects in food additives
