Abstract

This International Standard specifies a method for the determination of the genotoxic potential of water and waste water using the bacterial strains Salmonella enterica subsp. enterica serotype Typhimurium TA 98 and TA 100 in a fluctuation assay. This combination of strains is able to measure the genotoxicity of chemicals that induce point mutations (base pair substitutions and frameshift mutations) in genes coding for enzymes that are involved in the biosynthesis of the amino acid, histidine.

Begin

2025-02-11

WI

00230460

Planned document number

DIN EN ISO 11350

Project number

11905063

Responsible national committee

NA 119-09-05-09 AK - Hormonal effects (xenohormons) (ISO/TC 147/SC 5/WG 9)  

Responsible european committee

CEN/TC 230 - Water analysis  

Responsible international committee

ISO/TC 147/SC 5/WG 9 - Genotoxicity and endocrine effects  

draft standard

Water quality - Determination of the genotoxicity of water and waste water - Salmonella/microsome fluctuation test (Ames fluctuation test) (ISO 11350:2012); German and English version prEN ISO 11350:2025
2025-05
Order from DIN Media