DIN Standards Committee Water Practice
Water quality - Non-target screening of organic compounds in water using chromatography and mass spectrometry - Part 1: General guidelines
Abstract
This document describes the conditions for performing, validating and safeguarding non-target-screening of small organic compounds in water (drinking water, ground water and surface water) by chromatographic separation techniques with by mass spectrometry. This document can be applied to both liquid chromatography with high resolution mass spectrometry and gas chromatography with mass spectrometry. Both high and low resolution mass spectrometry can be applied, sometimes with some specific rules depending on the technique used with gas chromatography. The ISO 13808 serie is divided in three parts. The first part gives fundamental aspects in the use of chromatography in combination with mass spectrometry for non-target screening of small organic compounds in water. The second part gives the ultimate working procedure of non-target screening with liquid chromatography with high resolution mass spectrometry. The third part gives ultimate working procedure of non-target screening with gas chromatography with mass spectrometry. The second and third parts of this document refer to the reader to these guidelines for the basic principles of the method and for the configuration of the instruments. This first part of ISO 13808 serie is intended to show fundamental aspects in the use of chromatography in combination with mass spectrometry for non-target screening of small organic compounds in water drinking water, ground water, surface water. The standard can be applied to both liquid chromatography with high resolution mass spectrometry and gas chromatography with mass spectrometry. Both high and low resolution mass spectrometry can be applied with gas chromatography, sometimes with some specific rules depending on the technique used. The ultimate working procedure of non-target screening is described in two separated International Standard and provides criteria for carrying out, validating and safeguarding non-target screening. The individual parts of this Internal Standard refer to the reader to these guidelines for the basic principles of the method and for the configuration of the instruments.
Begin
2026-01-23
WI
00230480
Planned document number
prEN ISO 13808-1
Responsible national committee
NA 119-09-02-16 AK - LC-MS/MS methods
