NA 062

DIN Standards Committee Materials Testing

Standards [CURRENT]

DIN EN ISO 10808
Nanotechnologies - Characterization of nanoparticles in inhalation exposure chambers for inhalation toxicity testing (ISO 10808:2010); German version EN ISO 10808:2010

Title (German)

Nanotechnologien - Charakterisierung von Nanopartikeln in Inhalationskammern zur Prüfung auf Toxizität nach Inhalation (ISO 10808:2010); Deutsche Fassung EN ISO 10808:2010

Overview

This International Standard specifies requirements for, and gives guidance on, the characterization of airborne nanoparticles in inhalation exposure chambers for the purpose of inhalation toxicity studies in terms of particle mass, size distribution, number concentration and composition. This International Standard proposes a number of monitoring functions for the inhalation toxicity testing chamber, including a differential mobility analyzing system (DMAS) for measuring particle number, size, distribution, surface area and estimated mass dose, as well as morphological examination using transmission electron microscopy (TEM) or scanning electron microscopy (SEM) equipped with an energy dispersive X-ray analyzer (TEM-EDXA) for chemical composition. This International Standard also takes into account conventional mass dose monitoring and other physicochemical monitoring, for use when deemed a necessary parameter for toxicity determination. The method evaluates nano-sized particle surface area, mass dose, particle distribution, composition and dispersion to support effective analysis of inhalation toxicity testing results.

Document: references other documents

Document: referenced in other documents

Responsible national committee

NA 062-08-17-03 UA - Health and environmental aspects  

Responsible european committee

CEN/TC 352 - Nanotechnologies  

Edition 2011-04
Original language German
Translation English
Price from 91.80 €
Table of contents

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